Benzoyl chloride → 2-Benzoyl-3-p-methoxyphenylbenzofuran

HRID 1414626Notes

Reaction equation

HRID 1414626 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)=[CH:5][CH:4]=1.[C:18](Cl)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.COC1C=CC(C2OC3C=CC=CC=3C=2C(=O)C2C=CC(C)=CC=2)=CC=1>C(Cl)Cl>[C:18]([C:10]1[O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:9]=1[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 121700553-p-MethoxyphenylbenzofuranHCID 214879132-p-Methoxyphenyl-3-p-methylbenzoylbenzofuran

Product 1

HCID 105682682-Benzoyl-3-p-methoxyphenylbenzofuran

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Acylation of 3-p-methoxyphenylbenzofuran with benzoyl chloride and stannic chloride in methylene chloride as described in Example 1 for the preparation of 2-p-methoxyphenyl-3-p-methylbenzoylbenzofuran gives 2-benzoyl-3-p-methoxyphenylbenzofuran.

Sources & evidence

ORD record
ord-6a1bb5cfe9314cbb9144ced0cd41ed6d
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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