Pyridinium chloride → 2-Benzoyl-3-p-hydroxyphenylbenzofuran

HRID 1414627Notes

Reaction equation

HRID 1414627 reaction equation
[C:1]([C:9]1[O:10][C:11]2[CH:25]=[CH:24][CH:23]=[CH:22][C:12]=2[C:13]=1[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.N1C=CC=CC=1>>[C:1]([C:9]1[O:10][C:11]2[CH:25]=[CH:24][CH:23]=[CH:22][C:12]=2[C:13]=1[C:14]1[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 10176127Pyridinium chlorideHCID 105682682-Benzoyl-3-p-methoxyphenylbenzofuran

Product 1

HCID 125739642-Benzoyl-3-p-hydroxyphenylbenzofuran

Procedure

2-Benzoyl-3-p-methoxyphenylbenzofuran is demethylated with pyridine hydrochloride as previously described to give 2-benzoyl-3-p-hydroxyphenylbenzofuran, which upon reaction with 3-diethylaminopropyl chloride as described in Example 1, gives the title compound.

Sources & evidence

ORD record
ord-e59d94edda2f41099cc1fd5d604721b3
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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