3,5-Dimethylbenzoyl Chloride → 3-p-Methoxyphenyl-2-(3',5'-dimethylbenzoyl)benzofuran
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][CH:10]=2)=[CH:5][CH:4]=1.[CH3:18][C:19]1[CH:20]=[C:21]([CH:25]=[C:26]([CH3:28])[CH:27]=1)[C:22](Cl)=[O:23]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][C:10]=2[C:22](=[O:23])[C:21]2[CH:25]=[C:26]([CH3:28])[CH:27]=[C:19]([CH3:18])[CH:20]=2)=[CH:5][CH:4]=1Participants
3
Procedure
When 3-p-methoxyphenylbenzofuran is acylated with 3,5-dimethylbenzoyl chloride as described in the procedure of Example 1, 3-p-methoxyphenyl-2-(3',5'-dimethylbenzoyl)benzofuran is obtained.
Sources & evidence
- ORD record
- ord-ac968aba83b647048314400faa8907a6
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04001426
Reaction notes
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