3,5-Dimethylbenzoyl Chloride → HCID 21487907, compound

HRID 1414632Notes

Reaction equation

HRID 1414632 reaction equation
[Cl:1][CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[O:12][C:13]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][C:14]=3[CH:15]=2)=[CH:7][CH:6]=1.[CH3:22][C:23]1[CH:24]=[C:25]([CH:29]=[C:30]([CH3:32])[CH:31]=1)[C:26](Cl)=[O:27]>>[Cl:1][CH2:2][CH2:3][O:4][C:5]1[CH:6]=[CH:7][C:8]([C:11]2[O:12][C:13]3[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][C:14]=3[C:15]=2[C:26](=[O:27])[C:25]2[CH:29]=[C:30]([CH3:32])[CH:31]=[C:23]([CH3:22])[CH:24]=2)=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 810883,5-Dimethylbenzoyl ChlorideHCID 21487986HCID 21487986, compound

Product 1

HCID 21487907HCID 21487907, compound

Procedure

Acylation of 2-[4'-(2-chloroethoxy)phenyl]-5-methoxybenzofuran with 3,5-dimethylbenzoyl chloride as described in the procedure of Example 11 gives 2-[4'-(2-chloroethoxy)phenyl]-5-methoxy-3-(3',5'-dimethylbenzoyl)benzofuran.

Sources & evidence

ORD record
ord-e74fd8e2a8764074bfdcd07895f807a9
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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