HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → 6-Chloro-N-(3-chlorophenyl)-4H-3,1-benzothiazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | HCID 21484887 | HCID 21484887 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 6-Chloro-N-(3-chlorophenyl)-4H-3,1-benzothiazin-2-amine | HCID 21484885 | 52% |
Reaction Steps
A mixture of 6-chloro-2-methylthio-4H-3,1-benzothiazine (69 g, 0.30 mole) and 3-chloroaniline (38.2 g, 0.30 mole) in n-butanol (250 ml) was refluxed overnight. After cooling in ice, the solid was collected by filtration and recrystallized from ethanol-water mixture to give 48 g (52%) of title product, m.p. 174°-175°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002620 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-9e45bbc3043d4e4dbf230c8b4b2ec94a |
| Source note | uspto-grants-1977_01 |