p-Toluenesulfonic acid → (1,5-Dimethyl-1H-pyrrol-3-yl)(4-methylphenyl)methanone

Participants

Reaction Steps

A 1.0g sample of 1,2-dimethyl-5-p-toluoylpyrrole in 10g of dried p-toluenesulfonic acid heated at 105° C for 1 hour. The solution is then poured into sodium bicarbonate solution and extracted into chloroform. The chloroform is evaporated in vacuo and the residue is recrystallized from ethyl acetate to give 1,2-dimethyl-4-p-toluoylpyrrole as a tan solid; m.p. 117°-119° C.

Provenance & Evidence