HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Bromide → 1-Acetamido-4-benzyloxy-2-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-(4-hydroxy-2-nitrophenyl)acetamide | HCID 4024832 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Acetamido-4-benzyloxy-2-nitrobenzene | HCID 265888 | — |
Reaction Steps
2.94 G. of 1-acetamido-4-hydroxy-2-nitrobenzene, 5.13 g. of benzyl bromide and 4.2 g. anhydrous potassium carbonate are refluxed overnight in acetone with stirring, evaporated to dryness, the excess benzyl bromide removed under vacuum, water added and the product extracted with dichloromethane to give 1-acetamido-4-benzyloxy-2-nitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002640 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-ce06c513fcf0480d8862c83d43707fb2 |
| Source note | uspto-grants-1977_01 |