HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-Benzyloxy-2-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Acetamido-4-benzyloxy-2-nitrobenzene | HCID 265888 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Benzyloxy-2-nitroaniline | HCID 261497 | — |
Reaction Steps
The 1-acetamido-4-benzyloxy-2-nitrobenzene so produced is treated with sodium hydroxide in methanol, warmed briefly on a steam bath for about 15 minutes until the reaction is complete, diluted with water and extracted with dichloromethane to give 1-amino-4-benzyloxy-2-nitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002640 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-71100cffe25f4775a49f3f7fe74988d4 |
| Source note | uspto-grants-1977_01 |