HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-(2-Methoxyethoxy)benzene-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | 5-(2-Methoxyethoxy)-2-nitroaniline | HCID 22226981 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-(2-Methoxyethoxy)benzene-1,2-diamine | HCID 54249323 | — |
Reaction Steps
A mixture of 11 g. of 2-nitro-5-(2-methoxyethoxy) aniline, 220 ml. of methanol, 460 ml. of water, 40 g. sodium carbonate and 60 g. sodium hydrosulfite is refluxed for 15 minutes. The solution is concentrated, diluted with water and extracted with chloroform. Evaporation of the chloroform leaves 1,2-diamino-4-(2-methoxyethoxy) benzene as an oil, sufficiently pure for the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002640 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-e70dd23206a944d88fb6d64a853964fd |
| Source note | uspto-grants-1977_01 |