HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-2-nitroaniline → 2-Nitro-5-phenylthioaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-2-nitroaniline | HCID 6979 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Nitro-5-phenylthioaniline | HCID 170737 | — |
Reaction Steps
A mixture of 6.0 kg. of 1-amino-2-nitro-4-chlorobenzene and 7.2 kg. of potassium carbonate in 25 l. of DMF under nitrogen is treated with 4.0 kg. of thiophenol. The mixture is stirred for 2 hours, cooled, and diluted with 140 l. of ice water. The mixture is stirred for 1 hour, and 1-amino- 2-nitro-5-phenylthiobenzene is isolated by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002640 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-6971640f1cf54dc69577b178fac0414b |
| Source note | uspto-grants-1977_01 |