Phenylacetic Acid → HCID 86734394, compound

Participants

Reaction Steps

17.4 g (0.1 mol) of adipic acid dihydrazide and 27.2 g (0.2 mol) of phenylacetic acid are suspended in 230 ml of chlorobenzene, 2.0 g (0.025 mol) of pyridine are added and the mixture is heated to the boil. Thereafter 26.2 g (0.22 mol) of thionyl chloride are added dropwise, whereupon the vigorous reaction commences. The suspension turns slightly brown. After boiling for 1 hour it is cooled and filtered and the product is washed with methanol. N,N'-Diphenylacetyl-adipic acid dihydrazide of melting point 310°-312° C is thus obtained in 63% yield.

Provenance & Evidence