HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 68143211, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Gon-4-en-3-one, 13-ethyl-17-hydroxy-, (17beta)-(+-)- | HCID 10039774 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 68143211 | HCID 68143211 | — |
Reaction Steps
Reflux dl-13-ethyl-17β-hydroxygon-4-en-3-one (3.0 g) with acetic anhydride (45 cc), acetyl chloride (24 cc) and pyridine (2.4 cc) for 3 hours. Take to dryness under reduced pressure and partition the residue between benzene-ether and water. Triturate the crude product with hot ether to obtain dl-3,17-diacetoxy-13-ethylgona-3,5-diene (3.125 g), m.p. 148°-156°; λmax. KBr 5.68, 5.78, 6.0, 6.11 μ; λmax. EtOH 238 mμ (ε19,500).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002746 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-0b4e0a53f89c44b8a40686c27290be36 |
| Source note | uspto-grants-1977_01 |