Sodium Hydroxide → HCID 20390079, compound

HRID 1415114Notes

Reaction equation

HRID 1415114 reaction equation
[CH3:1][S:2][CH2:3][S:4][CH:5]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:6]([O:8]CSC)=[O:7].[OH-].[Na+]>C(O)C>[CH3:1][S:2][CH2:3][S:4][CH:5]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:6]([OH:8])=[O:7]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 86734401HCID 86734401, compound

Product 1

HCID 20390079HCID 20390079, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.9 gms. of DL-α-[[(methylthio)methyl]thio]benzene acetic acid, (methylthio)methyl ester are dissolved in 10 ml. of ethanol. 20 ml. of 1N alcoholic sodium hydroxide solution are added and the mixture is permitted to stand overnight. This is then concentrated, the residue is dissolved in water, the aqueous solution is extracted once with ether, then acidified and the oil is extracted with ether. After drying with magnesium sulfate and evaporating the solvent 1.8 gms. of DL-α-[[(methylthio)methyl]thio]benzeneacetic acid are obtained as an oil.

Workup

  1. concentrationThis is then concentrated
  2. dissolutionthe residue is dissolved in water
  3. extractionthe aqueous solution is extracted once with ether
  4. extractionthe oil is extracted with ether
  5. dry with materialAfter drying with magnesium sulfate
  6. customevaporating the solvent 1.8 gms

Sources & evidence

ORD record
ord-b75af90dae0941daa0483559a7515d55
Source dataset
uspto-grants-1977_01
Patent number
US04003893

Reaction notes

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