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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1415138Generated: November 1, 2026

7-chloro-3-ethyl-5-methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid, ethyl ester → 3,5-dimethyl-7-ethoxy-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester

https://huagongshe.com/reaction/1415138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-chloro-3-ethyl-5-methyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid, ethyl esterHCID 12387638—
Reactant7-chloro-3,5-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid ethyl esterHCID 12387640—
Product3,5-dimethyl-7-ethoxy-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl esterHCID 5429551178%

Reaction Steps

By replacing 7-chloro-3-ethyl-5-methyl-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester in Example 1 e with 7-chloro-3,5-dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid ethyl ester, 3,5-dimethyl-7-ethoxy-3H-imidazo-[4,5-b]pyridine-6-carboxylic acid, ethyl ester is obtained. Yield 78%, m.p. 85°-87° (ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04003908
Source datasetuspto-grants-1977_01
ORD IDord-3ede7d3445a44f1199fb7e9c7b2c23f6
Source noteuspto-grants-1977_01