HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 5-[1-Phenyl-1-(3-pyridyl)-3-(2-azabicyclo[2.2.2]oct-2-yl)propyl]-2-methyl-1,3,4-oxadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 178420261 | HCID 178420261 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 5-[1-Phenyl-1-(3-pyridyl)-3-(2-azabicyclo[2.2.2]oct-2-yl)propyl]-2-methyl-1,3,4-oxadiazole | HCID 12300666 | — |
Reaction Steps
2.0 Parts of 5-[1-phenyl-1-(3-pyridyl)-3-(2-azabicyclo[2.2.2]oct-2-yl)propyl]-1H-tetrazole was reacted with 4.0 parts of acetic anhydride in pyridine and refluxed for 2 hours to provide 5-[1-phenyl-1-(3-pyridyl)- 3-(2-azabicyclo[2.2.2]oct-2-yl)propyl]-2-methyl-1,3,4-oxadiazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04003904 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-bd9e15b036aa4df59babd7ca49cc0f6a |
| Source note | uspto-grants-1977_01 |