HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5,6-Tetrahydrophthalic anhydride → HCID 20541555, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5,6-Tetrahydrophthalic anhydride | HCID 12475 | — |
| Reactant | 4-Chloro-2-fluoroaniline | HCID 93898 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 20541555 | HCID 20541555 | — |
Reaction Steps
4.8 Parts of 4-chloro-2-fluoroaniline were added to a solution of 5 parts of 3,4,5,6-tetrahydrophthalic anhydride in 150 parts of diethyl ether and stirred for 1.5 hours. The solution was divided into two equal portions. One portion was evaporated under reduced pressure of 300 mm Hg. at 25° C to isolate 5.4 parts of 2-(4-chloro-2-fluorophenylaminocarbonyl)-1-cyclohexene-1-carboxylic acid as white crystals melting at 91°-93° C. The other portion was used in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04003926 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-717f1f7ef9d648bbb97ce3980b91a006 |
| Source note | uspto-grants-1977_01 |