Pyridinium chloride → HCID 21483899, compound

HRID 1415200Notes

Reaction equation

HRID 1415200 reaction equation
[CH:1]1([CH:6]2[CH2:15][CH2:14][C:13]3[C:8](=[C:9]([Cl:19])[C:10]([Cl:18])=[C:11]([O:16]C)[CH:12]=3)[C:7]2=[O:20])[CH2:5][CH2:4][CH2:3][CH2:2]1.Cl.N1C=CC=CC=1>O>[CH:1]1([CH:6]2[CH2:15][CH2:14][C:13]3[C:8](=[C:9]([Cl:19])[C:10]([Cl:18])=[C:11]([OH:16])[CH:12]=3)[C:7]2=[O:20])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 2

HCID 10176127Pyridinium chlorideHCID 21483939HCID 21483939, compound

Product 1

HCID 21483899HCID 21483899, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
180 °C

Procedure

2-Cyclopentyl-6-methoxy-7,8-dichloro-1-tetralone (6.58 g., 0.02 mole) is mixed with pyridine hydrochloride (60 g.) and the mixture is heated at 180° C. for one hour. The mixture is poured into water (ca. 400 ml.). The solid that separates is collected, washed with water and air dried to obtain 2-cyclopentyl-6-hydroxy-7,8-dichloro-1-tetralone.

Workup

  1. customThe solid that separates is collected
  2. washwashed with water and air
  3. customdried

Sources & evidence

ORD record
ord-af591a4df0884d22b73bb0dabc6a4b79
Source dataset
uspto-grants-1977_01
Patent number
US04003927

Reaction notes

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