Pyridinium chloride → HCID 21483904, compound

HRID 1415204Notes

Reaction equation

HRID 1415204 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]2[C:10](=[C:11]([Cl:14])[C:12]=1[Cl:13])[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2.Cl.N1C=CC=CC=1>O>[OH:2][C:3]1[CH:4]=[C:5]2[C:10](=[C:11]([Cl:14])[C:12]=1[Cl:13])[C:9](=[O:15])[CH2:8][CH2:7][CH2:6]2

Participants

4

Reactant 2

HCID 10176127Pyridinium chlorideHCID 14257701HCID 14257701, compound

Product 1

HCID 21483904HCID 21483904, compoundYield 43.3%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 6-methoxy-7,8-dichloro-1-tetralone (2.45 g.) and pyridine hydrochloride (25 g.) is heated at 180°-190° C. for two hours and then poured into water (500 ml.). The product is collected, washed with water, dried and crystallized from ethanol-water (3:2) to obtain 6-hydroxy-7,8-dichloro-1-tetralone (1 g.), melting point 243.5°-245.5° C.

Workup

  1. temperatureis heated at 180°-190° C. for two hours
  2. customThe product is collected
  3. washwashed with water
  4. customdried
  5. customcrystallized from ethanol-water (3:2)

Sources & evidence

ORD record
ord-3ce59132af18412b8b3d8a9e03707192
Source dataset
uspto-grants-1977_01
Patent number
US04003927

Reaction notes

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