HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylthiourea → 2-Chloroethyl [1-(3-phenylthioureido)-2-(p-chlorophenyl) ethyl]methylphosphinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylthiourea | HCID 676454 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | CID 4413076 | HCID 4413076 | — |
| Reactant | 2-(4-Chlorophenyl)acetaldehyde | HCID 11412502 | — |
| Reactant | HCID 14144590 | HCID 14144590 | — |
| Product | 2-Chloroethyl [1-(3-phenylthioureido)-2-(p-chlorophenyl) ethyl]methylphosphinate | HCID 53750179 | — |
Reaction Steps
This example shows the preparation of a phosphinate compound, i.e., a compound having two P--C bonds. It also shows the use of a thiourea as a reactant. When equimolar quantities of bis(2-chloroethyl) methylphosphonite, p-chlorophenylacetaldehyde, and phenylthiourea are warmed at 90°-110° C for 1 hour, 2-chloroethyl [1-(3-phenylthioureido)-2-(p-chlorophenyl) ethyl]methylphosphinate is formed. Hydrolysis gives the corresponding phosphinic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04003965 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-ccd4a847d5e843b68a0dd770090ea32c |
| Source note | uspto-grants-1977_01 |