HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 5,7-Dimethyl-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ethyl (imidazolidin-2-ylidene)acetate | HCID 12377942 | — |
| Reactant | Ethylideneacetoacetic acid ethyl ester | HCID 53428592 | — |
| Product | 5,7-Dimethyl-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester | HCID 12377954 | 58% |
Reaction Steps
Upon heating a solution of 6 g of ethylideneacetoacetic acid ethyl ester and 6 g of 2-carbethoxymethylideneimidazolidine in 50 ml of ethanol for 10 hours, 5,7-dimethyl-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester of melting point 138° (ethanol) is obtained. Yield: 58% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04004015 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-5bc08101f8d14ed29ecb3813f7f34870 |
| Source note | uspto-grants-1977_01 |