HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (imidazolidin-2-ylidene)acetate → 5-Methyl-7-(naphth-1-yl)-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (imidazolidin-2-ylidene)acetate | HCID 12377942 | — |
| Reactant | (1-Naphthylidene)acetoacetic acid ethyl ester | HCID 70607594 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Methyl-7-(naphth-1-yl)-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester | HCID 68119305 | 52% |
Reaction Steps
Heating a solution of 9.0 g of (naphth-1-ylidene)acetoacetic acid ethyl ester and 5.2 g of 2-carbethoxymethylideneimidazolidine in 60 ml of ethanol for 6 hours yields 5-methyl-7-(naphth-1-yl)-1,2,3,7-tetrahydroimidazolo[1,2-a]pyridine-6,8-dicarboxylic acid diethyl ester of melting point 169°-170° C (ethanol). Yield: 52% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04004015 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-4b5a7dc9c44347528879bf2fa393c4b2 |
| Source note | uspto-grants-1977_01 |