p-Toluenesulfonic acid → HCID 21481848, compound

Participants

Reaction Steps

3-Benzyloxy-2-methylpropane-1,2-diol (5.0g), 1,1-diethoxyethane (3.0g) and p-toluenesulphonic acid were heated at 110°-115° C with stirring until no more alcohol was evolved. The mixture was then heated at 140°-145° C for 15 minutes. After cooling, the mixture was dissolved in ether and the resulting solution was then washed with 5% potassium carbonate solution followed by water. The solution was dried over anhydrous magnesium sulphate and the solvent was removed under reduced pressure to yield a liquid which on distillation gave the desired product having a b.p. 81°-82° C at 0.3 mm Hg.

Provenance & Evidence