Oxalyl chloride → HCID 86734440, compound

Participants

Reaction Steps

9.7 grams of the thus-obtained isobutylmalonic acid monobenzyl ester were dissolved in 120 ml of absolute benzene. The solution was treated with 40 drops of dimethylformamide and subsequently, at 0°, with 6.64 ml of oxalyl chloride. After stirring at 0°-5° for 1 hour and for 30 minutes at 20°, the mixture was evaporated under reduced pressure and the residue re-evaporated once with benzene to yield isobutylmalonic acid monobenzyl ester chloride as an orange-red oil.

Provenance & Evidence