Acetaldehyde → HCID 53960399, compound

HRID 1415397Notes

Reaction equation

HRID 1415397 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:10][O:9][N:8]=[C:7]([N:11]([CH3:13])[NH2:12])[C:6]=2[CH:14]=1.[CH:15](=O)[CH3:16]>C1C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[CH2:10][O:9][N:8]=[C:7]([N:11]([CH3:13])[N:12]=[CH:15][CH3:16])[C:6]=2[CH:14]=1

Participants

4

Reactant 2

HCID 177AcetaldehydeHCID 21824527HCID 21824527, compound

Product 1

HCID 53960399HCID 53960399, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

To a solution of 3 g. of 6-chloro-4-(1-methylhydrazino)-1H-2,3-benzoxazine in 180 ml. of anhydrous benzene 1 g. of acetaldehyde in 30 ml. of anhydrous benzene is added. The mixture is allowed to stand for 2 hours, then the solvent is distilled off in vacuo and the residue recrystallized from isopropyl ether. Yield 2.4 g. (71.2%) of 6-chloro-4-(2-ethylidene-1-methylhydrazino)-1H-2,3-benzoxazine; m.p. 111°-112° C.

Workup

  1. distillationthe solvent is distilled off in vacuo
  2. customthe residue recrystallized from isopropyl ether

Sources & evidence

ORD record
ord-c8f788d071d542d79d55b6d8dc681f09
Source dataset
uspto-grants-1977_01
Patent number
US04005082

Reaction notes

Loading…