HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picilorex → HCID 86734443, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picilorex | HCID 191657 | — |
| Reactant | Ethanol, 1-bromo- | HCID 14202443 | — |
| Product | HCID 86734443 | HCID 86734443 | 65.6% |
Reaction Steps
The procedure of Example XXXV using 15 g of 2-cyclopropyl-4-(p-chlorophenyl)-5-methyl-pyrrolidine and 8.8 g of bromoethanol gives 6.6 g of N-hydroxyethyl-2-cyclopropyl-4-(p-chlorophenyl)-5-methylpyrrolidine hydrochloride as white crystals after recrystallisation from ethyl acetate -- acetone (50:50). Melting point = 175°-180° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04005103 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-4a6cdb599e2d4d79abd55b4ff5fa8a6d |
| Source note | uspto-grants-1977_01 |