4-Nitrophenol → 3,7-Dimethylocta-2,6-dienyl p-nitrophenyl ether

HRID 1415483노트

반응식

HRID 1415483 반응식
[CH:1]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][CH:4]=[C:3]([OH:10])[CH:2]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:17][C:18]([CH2:22][CH2:23][CH:24]=[C:25]([CH3:27])[CH3:26])=[CH:19][CH2:20]Br>CN(C)C=O.O>[N+:7]([C:6]1[CH:5]=[CH:4][C:3]([O:10][CH2:20][CH:19]=[C:18]([CH3:17])[CH2:22][CH2:23][CH:24]=[C:25]([CH3:27])[CH3:26])=[CH:2][CH:1]=1)([O-:9])=[O:8]

참가 물질

6

반응물 3

HCID 9804-NitrophenolHCID 11430Potassium CarbonateHCID 802281-Bromo-3,7-dimethylocta-2,6-diene

생성물 1

HCID 681251833,7-Dimethylocta-2,6-dienyl p-nitrophenyl ether

시약·촉매·용매 2

HCID 962Water용매HCID 6228Dimethylformamide용매

실험 절차

To a solution of p-nitrophenol (2 g.) in dimethylformamide (10 ml.) is added anhydrous potassium carbonate (2 g.) and 3,7-dimethylocta-2,6-dienyl bromide (3.1 g.). The reaction is kept at 50° for 12 hours, diluted with water and extracted with ether. The ethereal extract is washed with 5% aqueous sodium hydroxide and dried over sodium sulfate. The crude product is purified by distillation to yield 3,7-dimethylocta-2,6-dienyl p-nitrophenyl ether.

후처리

  1. extractionextracted with ether
  2. extractionThe ethereal extract
  3. washis washed with 5% aqueous sodium hydroxide
  4. dry with materialdried over sodium sulfate
  5. distillationThe crude product is purified by distillation

출처 및 근거

ORD 기록
ord-cbdfcba70f324427bc9a8af209185716
출처 데이터셋
uspto-grants-1977_01
특허 번호
US04005150

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