Isopropylamine → HCID 21482742, compound

HRID 1415506Notes

Reaction equation

HRID 1415506 reaction equation
[NH2:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([S:9](Cl)(=[O:11])=[O:10])=[CH:4][C:3]=1[Br:13].[CH:14]([NH2:17])([CH3:16])[CH3:15]>O>[NH2:1][C:2]1[C:7]([Br:8])=[CH:6][C:5]([S:9]([NH:17][CH:14]([CH3:16])[CH3:15])(=[O:11])=[O:10])=[CH:4][C:3]=1[Br:13]

Participants

4

Reactant 2

HCID 6363IsopropylamineHCID 21482735HCID 21482735, compound

Product 1

HCID 21482742HCID 21482742, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.0 G. of 4-amino-3,5-dibromobenzenesulfonyl chloride is added to a solution of 34 ml. of isopropylamine in 30 ml. of water. The resultant solution is stirred overnight at room temperature and poured onto 250 ml. of an ice/water mixture. The precipitate is filtered, washed with water and dried. The dried filtrate is recrystallized from isopropanol affording pure 4-amino-3,5-dibromo-N-isopropylbenzenesulfonamide, m.p. 181° to 183° C.

Workup

  1. additionpoured onto 250 ml
  2. filtrationThe precipitate is filtered
  3. washwashed with water
  4. customdried
  5. customThe dried filtrate is recrystallized from isopropanol affording pure 4-amino-3,5-dibromo-N-isopropylbenzenesulfonamide, m.p. 181° to 183° C.

Sources & evidence

ORD record
ord-814d6fb4aee940e4839a97f0d2e26c7b
Source dataset
uspto-grants-1977_01
Patent number
US04005199

Reaction notes

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