反应详情

N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-ethylenediamine is prepared by reacting 2-(4-methoxyphenyl)oxirane (37.5 g.) dissolved in methanol (52 cc.) with ethylenediamine (30 cc.) dissolved in a mixture of methanol (52 cc.) and water (20 cc.). On distillation under reduced pressure, a product (22.3 g.), b.p. 165°-169° C./0.2 mm.Hg, is obtained, which crystallises on cooling and melts at 68° C.

1. distillationOn distillation under reduced pressure
2. customa product (22.3 g.), b.p. 165°-169° C./0.2 mm.Hg, is obtained
3. customwhich crystallises
4. temperatureon cooling