1-Cyclohexylpiperidin-4-amine → N-(N-cyclohexyl-4-piperidinyl)-9-xanthenylamine

HRID 1415549Notes

Reaction equation

HRID 1415549 reaction equation
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([CH:8]2[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]2)[CH2:4][CH2:3]1.C(O[CH:18]1[C:31]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[O:25][C:24]2[C:19]1=[CH:20][CH:21]=[CH:22][CH:23]=2)(=O)C>C1(C)C=CC=CC=1>[CH:8]1([N:5]2[CH2:6][CH2:7][CH:2]([NH:1][CH:18]3[C:19]4[CH:20]=[CH:21][CH:22]=[CH:23][C:24]=4[O:25][C:26]4[C:31]3=[CH:30][CH:29]=[CH:28][CH:27]=4)[CH2:3][CH2:4]2)[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 47782391-Cyclohexylpiperidin-4-amineHCID 125434549-Acetoxyxanthene

Product 1

HCID 21482826N-(N-cyclohexyl-4-piperidinyl)-9-xanthenylamine

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Refluxing 4-amino-1-cyclohexylpiperidine and 9-acetoxyxanthene in dry toluene for 24 hours, then working up as in Example 1 gives N-(N-cyclohexyl-4-piperidinyl)-9-xanthenylamine.

Sources & evidence

ORD record
ord-195514c5f7ac46738ec7c495ebbbfd1c
Source dataset
uspto-grants-1977_01
Patent number
US04005208

Reaction notes

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