反应详情

A mixture of 5 g. of N-(N-ethoxycarbonyl-4- piperidinyl)-9-xanthenylamine, prepared as in Example 14, and 25 g. of potassium hydroxide in 125 ml. of aqueous ethanol is heated at reflux for three hours and then cooled and added with stirring to 1 liter of ice water. The mixture is extracted with ether and the extracts dried and concentrated in vacuo to give N-(4-piperidinyl)-9-xanthenylamine.

1. additionA mixture of 5 g
2. temperatureat reflux for three hours
3. temperaturecooled
4. additionadded
5. extractionThe mixture is extracted with ether
6. customthe extracts dried
7. concentrationconcentrated in vacuo