9-Acetoxyxanthene → N-(N-cyclopropyl-4-piperidinyl)-9-xanthenylamine

HRID 1415555Notes

Reaction equation

HRID 1415555 reaction equation
[NH2:1][CH:2]1[CH2:7][CH2:6][N:5]([CH:8]2[CH2:10][CH2:9]2)[CH2:4][CH2:3]1.C(O[CH:15]1[C:28]2[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=2[O:22][C:21]2[C:16]1=[CH:17][CH:18]=[CH:19][CH:20]=2)(=O)C>C1(C)C=CC=CC=1>[CH:8]1([N:5]2[CH2:6][CH2:7][CH:2]([NH:1][CH:15]3[C:16]4[CH:17]=[CH:18][CH:19]=[CH:20][C:21]=4[O:22][C:23]4[C:28]3=[CH:27][CH:26]=[CH:25][CH:24]=4)[CH2:3][CH2:4]2)[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 125434549-AcetoxyxantheneHCID 162276441-Cyclopropylpiperidin-4-amine

Product 1

HCID 21482905N-(N-cyclopropyl-4-piperidinyl)-9-xanthenylamine

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Refluxing 4-amino-1-cyclopropylpiperidine and 9-acetoxyxanthene in dry toluene for 24 hours, then working up as in Example 1 gives N-(N-cyclopropyl-4-piperidinyl)-9-xanthenylamine.

Sources & evidence

ORD record
ord-f6221c87eebb48338e05bf6bdf4d6199
Source dataset
uspto-grants-1977_01
Patent number
US04005208

Reaction notes

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