Diethyl Ether → 2,3-Dihydroxybutanedioate

Participants

Reaction Steps

To a solution of 1.1 g. of N-(N-ethyl-3-piperidinyl)-9-xanthenylamine in 8 ml. of tetrahydrofuran and 50 ml. of diethyl ether at -5° C. was added 538 mg. of levo tartaric acid in 32 ml. of tetrahydrofuran. The resulting precipitate was allowed to stand one hour, filtered off, washed twice with 100 ml. portions of ether and air-dried to give N-(N-ethyl-3-piperidinyl)-9-xanthenylamine, tartrate, hydrate m.p. 146°-148° C. (dec.)

Provenance & Evidence