Bromoacetyl bromide → N-(4-methoxycarbonylamino-2-nitrophenyl)-2-bromoacetamide

Participants

Reaction Steps

4-Methoxycarbonylamino-2-nitroaniline (30 g) was dissolved in toluene (300 ml) and the solution treated with bromoacetyl bromide (28.7 g). The mixture was refluxed for 3 hours and toluene (300 ml) was added. The hot mixture was filtered and the filtrate allowed to cool to give N-(4-methoxycarbonylamino-2-nitrophenyl)-2-bromoacetamide (30 g), m.p. 160°-162° C.

Provenance & Evidence