Sodium Carbonate → HCID 15411601, compound

HRID 1415701Notes

Reaction equation

HRID 1415701 reaction equation
Br[C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:24])[N:7]3[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([NH:18][CH2:19][CH2:20][N:21]([CH3:23])[CH3:22])=[O:17])[C:8]3=[N:9]2)=[CH:4][CH:3]=1.[N:25]1[CH:30]=[CH:29][CH:28]=[C:27](B(O)O)[CH:26]=1.C(=O)([O-])[O-].[Na+].[Na+]>C1(C)C=CC=CC=1>[CH3:22][N:21]([CH3:23])[CH2:20][CH2:19][NH:18][C:16]([C:12]1[C:8]2=[N:9][C:10]3[C:5]([C:6](=[O:24])[N:7]2[CH:15]=[CH:14][CH:13]=1)=[CH:4][CH:3]=[C:2]([C:27]1[CH:26]=[N:25][CH:30]=[CH:29][CH:28]=1)[CH:11]=3)=[O:17]

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 27343783-Pyridinylboronic acidHCID 70113029HCID 70113029, compound

Product 1

HCID 15411601HCID 15411601, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The procedure of Example 6 was used with the product of Example 14 (39 mg, 0.1 mmol), product of Example 4 (123 mg, 1.0 mmol), tetrakis(triphenylphospine)palladium(0) (29 mg, 0.025 mmol), 2 M sodium carbonate solution (0.5 ml, 1.0 mmol), and toluene (5 ml).

Sources & evidence

ORD record
ord-1ca56f99d3254d4aa3800d0bc86eb42c
Source dataset
uspto-grants-1999_06
Patent number
US05908840

Reaction notes

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