HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 4-Chloro-furo[3,4-c]quinoline-1,3-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 2-Oxo-1,2-dihydroquinoline-3,4-dicarboxylic acid | HCID 804596 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Product | 4-Chloro-furo[3,4-c]quinoline-1,3-dione | HCID 54104238 | — |
Reaction Steps
A mixture of 2(1H)-Oxo-quinoline-3,4-dicarboxylic acid (2.0 g), phosphorous oxychloride (10 mL) and 8 drops of dimethyl formamide was refluxed with stirring for 20 min. The reaction mixture was concentrated in vacuo and the residue treated with ice water to afford 4-Chloro-furo[3,4-c]quinoline-1,3-dione as a tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05908932 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-e109e03336af433fa8fa375b747c071b |
| Source note | uspto-grants-1999_06 |