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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1415735Generated: October 26, 2026

1-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrrole → 3-Benzoylpropionitrile

https://huagongshe.com/reaction/1415735

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Methoxyphenyl)-4-Methyl-2-(4-sulfamoylphenyl)pyrroleHCID 21862793—
Reactant2-(3-Chloro-4-methoxyphenyl)-4-methyl-1-(4-sulfamoylphenyl)pyrroleHCID 21862846—
Product3-BenzoylpropionitrileHCID 138465—
Product4-Methyl-1-(4-methylthiophenyl)-2-(4-sulfamoylphenyl)pyrroleHCID 9928749—

Reaction Steps

In this Step, a phenacyl acetonitrile compound of formula (17) is prepared by alkylating the cyano compound of formula (16) with a phenacyl halide compound of formula (7). This reaction is essentially the same as and may be carried out in the same manner as and using the same reagents and reaction conditions as Step B3 of Method B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05908858
Source datasetuspto-grants-1999_06
ORD IDord-a257620a77224c62b266e2081366570a
Source noteuspto-grants-1999_06