4-Fluoroaniline → HCID 54472719, compound

HRID 1415763Notes

Reaction equation

[F:1][C:2]([F:18])([F:17])[C:3](=O)[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=1)=O.[F:19][C:20]1[CH:26]=[CH:25][C:23]([NH2:24])=[CH:22][CH:21]=1>>[F:1][C:2]([F:18])([F:17])[C:3]1[N:24]([C:23]2[CH:25]=[CH:26][C:20]([F:19])=[CH:21][CH:22]=2)[C:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][CH:9]=2)=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 97314-Fluoroaniline

HCID 54123519HCID 54123519, compound

Product 1

HCID 54472719HCID 54472719, compoundYield 42%

Procedure

Following a procedure similar to that described in Example 43(iii), but using 5,5,5-trifluoro-1-(4-methylthiophenyl)pentane-1,4-dione [prepared as described in step (ii) above] and 4-fluoroaniline as starting materials, the title compound was obtained as a pale brown oily substance (yield 42%).

Sources & evidence

ORD record: ord-bed88713f3dc4a58ab9ca20e764c2b7a
Source dataset: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05908858

Reaction notes

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