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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1415778Generated: November 1, 2026

Acrolein → 1-(4-Methylphenyl)-2-(4-sulfamoylphenyl)pyrrole

https://huagongshe.com/reaction/1415778

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcroleinHCID 7847—
Reactantalpha-(4-Methylanilino)-alpha-(4-sulfamoylphenyl)acetonitrileHCID 21862835—
Product1-(4-Methylphenyl)-2-(4-sulfamoylphenyl)pyrroleHCID 21862830—

Reaction Steps

Following a procedure similar to that described in Example 1(iii), but using α-(4-methylanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a pale brown powder (yield 28%), melting at 131-134° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05908858
Source datasetuspto-grants-1999_06
ORD IDord-d8ec8db41ce64236bb9fe1ff5b0cc16f
Source noteuspto-grants-1999_06