Acrolein → HCID 21862816, compound

HRID 1415783Notes

Reaction equation

HRID 1415783 reaction equation
[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]([NH:7][CH:8]([C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:13][CH:12]=2)[C:9]#N)=[CH:5][CH:4]=1.[CH:23]([CH:25]=C)=O>>[CH3:1][O:2][C:3]1[CH:22]=[CH:21][C:6]([N:7]2[CH:25]=[CH:23][CH:9]=[C:8]2[C:11]2[CH:16]=[CH:15][C:14]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:13][CH:12]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 7847AcroleinHCID 21862763HCID 21862763, compound

Product 1

HCID 21862816HCID 21862816, compound

Procedure

Following a procedure similar to that described in Example 1(iii), but using α-(4-methoxyanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and acrolein as starting materials, the title compound was obtained as a yellow powder (yield 9%), melting at 112-114° C.

Sources & evidence

ORD record
ord-f1329d808f83405da80cc6b1b083cd6f
Source dataset
uspto-grants-1999_06
Patent number
US05908858

Reaction notes

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