Sulfanilamide → HCID 21862747, compound

HRID 1415787Notes

Reaction equation

[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([C:6](=O)[CH2:7][CH:8]([CH3:11])[CH:9]=O)=[CH:4][CH:3]=1.[S:15]([C:19]1[CH:25]=[CH:24][C:22]([NH2:23])=[CH:21][CH:20]=1)(=[O:18])(=[O:17])[NH2:16]>>[Cl:1][C:2]1[CH:14]=[CH:13][C:5]([C:6]2[N:23]([C:22]3[CH:24]=[CH:25][C:19]([S:15](=[O:18])(=[O:17])[NH2:16])=[CH:20][CH:21]=3)[CH:9]=[C:8]([CH3:11])[CH:7]=2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 5333Sulfanilamide

HCID 21862891HCID 21862891, compound

Product 1

HCID 21862747HCID 21862747, compound

Procedure

Following a procedure similar to that described in Example 64(iii), but using 2-(4-chlorophenacyl)propionaldehyde [prepared as described in step (ii) above] and 4-sulfamoylaniline as starting materials, the title compound was obtained as a pale brown powder (yield 35%), melting at 196-198° C.

Sources & evidence

ORD record: ord-12c681ee31a34fa283d467b9400ced7e
Source dataset: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05908858

Reaction notes

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