Methacrolein → HCID 21862851, compound

HRID 1415795Notes

Reaction equation

HRID 1415795 reaction equation
[CH2:1]([O:4][C:5]1[CH:10]=[CH:9][C:8]([CH:11]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([S:21](=[O:24])(=[O:23])[NH2:22])=[CH:17][CH:16]=2)[C:12]#N)=[CH:7][CH:6]=1)[CH2:2][CH3:3].O=[CH:26][C:27](=C)[CH3:28]>>[CH3:28][C:27]1[CH:12]=[C:11]([C:8]2[CH:9]=[CH:10][C:5]([O:4][CH2:1][CH2:2][CH3:3])=[CH:6][CH:7]=2)[N:14]([C:15]2[CH:20]=[CH:19][C:18]([S:21](=[O:24])(=[O:23])[NH2:22])=[CH:17][CH:16]=2)[CH:26]=1

Participants

3

Reactant 2

HCID 6562MethacroleinHCID 21862812HCID 21862812, compound

Product 1

HCID 21862851HCID 21862851, compound

Procedure

Following a procedure similar to that described in Example 1(iii), but using α-(4-propoxyphenyl)-α-(4-sulfamoylanilino)acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a pale brown powder (yield 5%), melting at 142-145° C.

Sources & evidence

ORD record
ord-2fe520ae05bc498eb6ebeda192be3753
Source dataset
uspto-grants-1999_06
Patent number
US05908858

Reaction notes

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