Methacrolein → HCID 21862898, compound

HRID 1415807Notes

Reaction equation

HRID 1415807 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH:9]([NH:12][C:13]1[CH:18]=[CH:17][C:16]([S:19](=[O:22])(=[O:21])[NH2:20])=[CH:15][CH:14]=1)[C:10]#N.O=[CH:24][C:25](=C)[CH3:26]>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1[N:12]([C:13]2[CH:18]=[CH:17][C:16]([S:19](=[O:22])(=[O:21])[NH2:20])=[CH:15][CH:14]=2)[CH:24]=[C:25]([CH3:26])[CH:10]=1

Participants

3

Reactant 2

HCID 6562MethacroleinHCID 21862884HCID 21862884, compound

Product 1

HCID 21862898HCID 21862898, compound

Procedure

Following a procedure similar to that described in Example 1(iii), but using α-(2,4-difluorophenyl)-α-(4-sulfamoylanilino)acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a pale brown powder (yield 32%), melting at 170-172° C.

Sources & evidence

ORD record
ord-8acf1da3c60a4eea86d76e5ebb713464
Source dataset
uspto-grants-1999_06
Patent number
US05908858

Reaction notes

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