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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1415817Generated: October 27, 2026

Trimethylsilyl cyanide → alpha-(3,4-Dimethylphenyl)-alpha-(4-sulfamoylanilino)acetonitrile

https://huagongshe.com/reaction/1415817

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethylsilyl cyanideHCID 82115—
ReactantN-(3,4-Dimethylbenzylidene)-4-sulfamoylanilineHCID 21862821—
Productalpha-(3,4-Dimethylphenyl)-alpha-(4-sulfamoylanilino)acetonitrileHCID 21862877—

Reaction Steps

Following a procedure similar to that described in Example 1(ii), but using N-(3,4-dimethylbenzylidene)-4-sulfamoylaniline [prepared as described in step (i) above] and trimethylsilyl cyanide as starting materials, the title compound was obtained as a slightly yellow powder (yield 91%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05908858
Source datasetuspto-grants-1999_06
ORD IDord-b37d1726e620467d9080b10f00ba6219
Source noteuspto-grants-1999_06