Methacrolein → HCID 54279024, compound

HRID 1415834Notes

Reaction equation

[CH2:1]([S:3][C:4]1[CH:23]=[CH:22][C:7]([NH:8][CH:9]([C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=2)[C:10]#N)=[CH:6][CH:5]=1)[CH3:2].O=[CH:25][C:26](=C)[CH3:27]>>[CH2:1]([S:3][C:4]1[CH:23]=[CH:22][C:7]([N:8]2[CH:25]=[C:26]([CH3:27])[CH:10]=[C:9]2[C:12]2[CH:17]=[CH:16][C:15]([S:18](=[O:21])(=[O:20])[NH2:19])=[CH:14][CH:13]=2)=[CH:6][CH:5]=1)[CH3:2]

Participants

Reactant 2

HCID 6562Methacrolein

HCID 21862890HCID 21862890, compound

Product 1

HCID 54279024HCID 54279024, compound

Procedure

Following a procedure similar to that described in Example 1(iii), but using α-(4-ethylthioanilino)-α-(4-sulfamoylphenyl)acetonitrile [prepared as described in step (ii) above] and methacrolein as starting materials, the title compound was obtained as a slightly yellow powder (yield 69%), melting at 139-141° C.

Sources & evidence

ORD record: ord-dd5499a84a2140feb79dd6e6aa5a6fd6
Source dataset: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05908858

Reaction notes

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