Methanol → HCID 178498455, compound

Participants

Reaction Steps

10 mL of methanol at 0° C. was treated dropwise with 1 mL acetyl chloride, followed by addition of 2.0 g (17.84 mmol) of 4-pyrazolecarboxylic acid, followed by warming the mixture at reflux for 18 h. The solution was cooled and concentrated in vacuo to afford 2.6 g (90%) of the title compound as a white solid. 1H NMR (CD3OD) δ 8.25, 3.86.

Provenance & Evidence