HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(3-chloropropoxy)-1H-indole → 1-(4-Indolyloxy)-3-[4-hydroxy-4-(6-benzyloxynaphth-2-yl)piperidine-1-yl]propane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(3-chloropropoxy)-1H-indole | HCID 11694169 | — |
| Reactant | 4-Hydroxy-4-(6-benzyloxynaphth-2-yl)piperidine | HCID 54231929 | — |
| Product | 1-(4-Indolyloxy)-3-[4-hydroxy-4-(6-benzyloxynaphth-2-yl)piperidine-1-yl]propane | HCID 67573274 | 30% |
Reaction Steps
Beginning with 0.189 gm (0.90 mMol) 1-(4-indolyloxy)-3-chloropropane and 0.300 gm (0.90 mMol) 4-hydroxy-4-(6-benzyloxynaphth-2-yl)piperidine, 0.137 gm (30%) of the title compound was recovered as a white solid by the procedure described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05912256 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-ae7737eeaacc44b7afb7dfc8092cf1f0 |
| Source note | uspto-grants-1999_06 |