HCID 9803445, compound → HCID 9803444, compound

HRID 1416224Notes

Reaction equation

HRID 1416224 reaction equation
[CH:1]([C:4]1[CH:27]=[CH:26][C:7]([C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:17][CH2:18][N:19]([CH:23]([CH3:25])[CH3:24])[CH:20]([CH3:22])[CH3:21])=[N:14][N:15]=2)=[O:9])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[ClH:28].CO>CO>[ClH:28].[CH:1]([C:4]1[CH:27]=[CH:26][C:7]([C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:17][CH2:18][N:19]([CH:23]([CH3:25])[CH3:24])[CH:20]([CH3:21])[CH3:22])=[N:14][N:15]=2)=[O:9])=[CH:6][CH:5]=1)([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 9803445HCID 9803445, compoundHCID 21893726Hydrochloride methanol

Product 1

HCID 9803444HCID 9803444, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(4-Isopropylbenzoyl)amino-5-diisopropylaminoethylthio-1,3,4-thiadiazole (1.2 g) was dissolved in methanol (50 ml) and the solution, with hydrochloric acid-methanol (10 ml) added thereto, was stirred for 10 minutes at room temperature. The reaction mixture was concentrated under a vacuum. The resulting solid was recrystallized from n-hexane/ethanol, thereby yielding 1.3 g of the aimed compound.

Workup

  1. concentrationThe reaction mixture was concentrated under a vacuum
  2. customThe resulting solid was recrystallized from n-hexane/ethanol

Sources & evidence

ORD record
ord-1e9e45e45d0d44d8a73a626047644d88
Source dataset
uspto-grants-1999_06
Patent number
US05912258

Reaction notes

Loading…