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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 141625Generated: October 25, 2026

Tetrahydrofuran → 4-[5-[1-[4-Cyano-3-(trifluoromethyl)phenyl]-2,5-dihydro-4-methyl-2,5-dioxo-1H-pyrrol-3-yl]pentyl]-N-[4-(dimethylamino)phenyl]piperazine-1-carboxamide

https://huagongshe.com/reaction/141625

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
Reactant4-(Dimethylamino)phenyl isocyanateHCID 2733372—
Reactant4-[2,5-dihydro-3-methyl-2,5-dioxo-4-[5-(piperazin-1-yl)pentyl]-1H-pyrrol-1-yl]-2-(trifluoromethyl)benzonitrileHCID 22562427—
Product4-[5-[1-[4-Cyano-3-(trifluoromethyl)phenyl]-2,5-dihydro-4-methyl-2,5-dioxo-1H-pyrrol-3-yl]pentyl]-N-[4-(dimethylamino)phenyl]piperazine-1-carboxamideHCID 22562733—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-0673afbc527b47b79313266a51f6bf92
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)