Benzene, 1-(bromomethyl)-3-nitro- → HCID 10688306, compound

HRID 1416400Notes

Reaction equation

HRID 1416400 reaction equation
O=[C:2]1[CH2:6]N(CC([O-])=O)C(=O)N1.[N+:12]([C:15]1[CH:16]=[C:17]([CH:31]=[CH:32][CH:33]=1)[CH2:18][N:19]1[C:23](=[O:24])[C:22](=[O:25])[N:21]([CH2:26][C:27]([OH:29])=[O:28])[C:20]1=C)([O-:14])=[O:13].[N+](C1C=C(C=CC=1)CBr)([O-])=[O:35].[N+](C1C=C(C=CC=1)CN1C(=O)C(=O)N(CC(O)=O)C1=S)([O-])=O>>[OH:25][CH:22]1[N:21]([CH2:26][C:27]([O:29][CH2:2][CH3:6])=[O:28])[C:20](=[O:35])[N:19]([CH2:18][C:17]2[CH:31]=[CH:32][CH:33]=[C:15]([N+:12]([O-:14])=[O:13])[CH:16]=2)[C:23]1=[O:24]

Participants

5

Reactant 4

HCID 77568Benzene, 1-(bromomethyl)-3-nitro-HCID 7219893HCID 7219893, compoundHCID 10638264HCID 10638264, compoundHCID 106396263-(3-Nitrobenzyl)-4,5-dioxo-2-thioxoimidazolidine-1-acetic acid

Product 1

HCID 10688306HCID 10688306, compound

Procedure

The above-prepared dioxoimidazolidine-1-acetate product of paragraph (1) was condensed with 3-nitrobenzyl bromide in the same manner as mentioned in Example 8 paragraph (2) to give ethyl 5-hydroxy-3-(3-nitrobenzyl)-2,4-dioxoimidazolidine-1-acetate.

Sources & evidence

ORD record
ord-4223fc2f68444fa384ab765a81c86ac8
Source dataset
uspto-grants-1999_06
Patent number
US05912261

Reaction notes

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