HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetate → HCID 53831110, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetate | HCID 175 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Quinazoline | HCID 9210 | — |
| Reactant | Fumarate | HCID 5460307 | — |
| Reactant | HCID 53859577 | HCID 53859577 | — |
| Reactant | HCID 54302337 | HCID 54302337 | — |
| Reactant | HCID 54302338 | HCID 54302338 | — |
| Reactant | HCID 57153789 | HCID 57153789 | — |
| Product | HCID 53831110 | HCID 53831110 | — |
Reaction Steps
Among the above quinazoline compounds (I-B), preferred ones are (10B) 4-[(3R)-(3,4-dihydroxybutan-1-yl) oxy]-2-(1-piperazinyl)quinazoline, (6B) 4-[(2RS,3RS)-(2,3-dihydroxybutan-1-yl)oxy]-2-(1-piperazinyl)quinazoline, (7B) 4-[(2S,3S)-(2,3-dihydroxybutan-1-yl)oxy]-2-(1-piperazinyl)quinazoline, (8B) 4-[(2R,3R)-(2,3-dihydroxybutan-1-yl)oxy]-2-(1-piperazinyl)quinazoline, and their salts such as hydrochloride, acetate, fumarate, particularly hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05912247 |
| Source dataset | uspto-grants-1999_06 |
| ORD ID | ord-cef2c4cec20941838170d2e01b842512 |
| Source note | uspto-grants-1999_06 |